**Education and Professional Experience:** 2008.07-2011.07 Sun Yat-sen University Cancer Center, Department of Radiation Oncology, Resident Physician 2011.07-2017.12 The First Affiliated Hospital, Sun Yat-sen University, Department of Radiation Oncology, Attending Physician 2017.12-Present The First Affiliated Hospital, Sun Yat-sen University, Department of Radiation Oncology, Associate Chief Physician **Professional Affiliations:** Standing Committee Member, Oncology Professional Committee, Guangdong Provincial Clinical Medical Association Standing Committee Member, Multidisciplinary Comprehensive Diagnosis and Treatment of Tumors Professional Committee, Guangdong Provincial Primary Medical Association **Publications:** Published 19 papers in domestic and international academic journals as first author (including co-first author) and corresponding author (including co-corresponding author). Participated in and led multiple projects funded by the National Natural Science Foundation of China, Provincial Science and Technology Plans, and Departmental/ Bureau-level Scientific Research Projects. **Current Research Projects:** 1. Molecular mechanism of gemcitabine (GEM) activating EB virus lytic replication, Guangdong Provincial Medical Science and Technology Research Fund Project 2. Study on the effect of DNA-PKcs gene knockout and its inhibitor on non-homologous end joining repair of DNA double-strand breaks, National Natural Science Foundation of China **Major Publications (First/Co-first/Corresponding Author):** (1) YuFeng Ren, YuanHong Gao, XinPing Cao,et al., 3D-CT implanted interstitial brachytherapy for T2b NPC. Radiation Oncology 2010, 5:113 (2) YuFeng Ren, Yanfang Li, Jihong Liu. A modified shorten administration schedule for neoadjuvant chemotherapy with irinotecan and cisplatin in locally advanced cervical cancer. Int J Gynecol Cancer 2011;21: 685-689 (3) YuFeng Ren, XinPing Cao, Jia Xu,et al.,3D-image-guided high-dose-rate intracavitary brachytherapy for salvage treatment of locally persistent NPC. Radiation Oncology 2013,8:165 (4) Yan Xiong, YuFeng Ren, Jia Xu, et al.,.Enhanced external counterpulsation inhibits endothelial apoptosis via modulation of BIRC2 and Apaf-1 genes in porcine hypercholesterolemia. Int J Cardiol 2013, 11: 033 (5) YuFeng Ren, QuanCheng Zhao, Hui Liu,et al.,3D-image-guided HDR-BT versus 2D HDR-BT after external beam radiotherapy for early T-stage NPC.BMC Cancer.2014, 14:894 (6) Jia Xu, YuFeng Ren, Xue Xu,et al., Schistosoma japonicum tegumental protein 20.8role in reproduction through its calcium binding ability. Parasitol Res,2014,113:491–497 (7) Sangang Wu, Juan Zhou, YuFeng Ren,et al., Tumor location is a prognostic factor for survival of Chinese women with T1-2N0M0 breast cancer. International Journal of Surgery 2014,12:394 (8) YuFeng Ren, Huizhi Qiu, Yujie Yuan, ,et al.,Evaluation of 7th Edition of AJCC Staging System for Nasopharyngeal Carcinoma.Journal of Cancer.2017,8(9):1665 (9) Jinning Ye, Yufeng Ren, Jianhui Chen,et al., Prognostic Significance of Preoperative and Postoperative Complement C3 Depletion in Gastric Cancer: A Three-Year Survival Investigation. BioMed Research International. 2017(2)14. (10) Li Ma, Guang, Yu Luo, YuFeng Ren, ,et al.,Concurrent chemoradiotherapy combined with enteral nutrition support: a radical treatment strategy for esophageal squamous cell carcinoma patients with malignant fistulae.CJC.(2017) 36:8 (11) Shaoqing Niu, Ge Wen, Yufeng Ren,et al., Predictive Value of Primary TumorSite for LocoregionalRecurrence in Early Breast Cancer Patients with One toThree Positive Axillary Lymphadenophy. Journal of Cancer 2017,(4).8 (12) Jun D,Tian Z,Yufeng Ren,et al.,Inhibiting DNA-PKcs in a non-homologus end-joining pathway in response to DNA double-strand breaks.Oncotarget.2017.07. (13) Ren,YF;Ye,JN;Zhang,J,et al.,Adjuvant radiation therapy for positive lymph nodes after resection of esophageal squamous cell carcinoma: Can it earn promising benefits within long-term follow-up?Annals of Oncology.(Abstract).2017:28:3:P-066 (14) Ye,JN; Ren,YF; Wang,Y,et al.,The optimal application of transrectal ultrasound in staging of rectal cancer following neoadjuvant therapy: A pragmatic study for accuracy investigation. Annals of Oncology.(Abstract).2017(28):3: P-365 (15) Y.Ren,J.Ye,W.Xiong,J,et al., Adjuvant radiotherapy for positive lymph nodes of oesophageal squamous cell carcinoma:can it earn promising benefits at long-term follow-up? Cancer Radiother, 2018:1278. (16) Yufeng Ren,Jinning Ye,Yan Wang,et al.,The Optimal Application of Transrectal Ultrasound in Staging of Rectal Cancer Following Neoadjuvant Therapy: A Pragmatic Study for Accuracy Investigation. Journal of Cancer 2018 (9) (17) Jinning Ye, Yufeng Ren, Zhewei Wei,et al., External validation of a modified 8th AJCC TNM system for advanced gastric cancer: Long-term results in southern China. Surgical Oncology 27 (2018) 146-153. (18) Jun Dong, Yufeng Ren , Tian Zhang,,et al., Inactivation of DNA-PK by knockdown DNA-PKcs or NU7441 impairs non-homologous end-joining of radiation-induced double strand break repair. ONCOLOGY REPORTS,2018 39: 912 (19) Yujie Yuan, Jinning Ye, Yufeng Ren.Exploration of the optimal treatment regimes for Esthesioneuroblastoma: a single center experience in China. Journal of Cancer.2018;9(1): 174