**Education and Professional Experience:** 1997.09 - 2004.07 Seven-year Clinical Medicine Program (English Class), Zhongshan School of Medicine, Sun Yat-sen University 2004.07 - 2005.04 Resident, Department of Cardiothoracic Surgery, The First Affiliated Hospital, Sun Yat-sen University 2005.05 - 2009.11 Resident & Chief Resident, Department of Cardiac Surgery, The First Affiliated Hospital, Sun Yat-sen University 2009.12 - 2010.08 Attending Physician, Department of Cardiac Surgery, The First Affiliated Hospital, Sun Yat-sen University 2010.09 - 2013.07 Doctoral Candidate & Attending Physician, Department of Cardiac Surgery, The First Affiliated Hospital, Sun Yat-sen University 2013.08 - 2016.12 Attending Physician & District Chief, Department of Cardiac Surgery, The First Affiliated Hospital, Sun Yat-sen University 2017.01 - Present Associate Chief Physician & District Chief, Department of Cardiac Surgery, The First Affiliated Hospital, Sun Yat-sen University 2019.05 - 2021.04 Visiting Scholar, University of Virginia, USA **Professional Affiliations:** Vice Chairman, Youth Committee of Cardiovascular Surgery Branch, Guangdong Medical Association (2nd Session, 2020) **Publications:** 1. Xu Z, Zhang SY, Huang M, Hu R, LL, Cen H, Wang ZP, Ou JS, Yin SL, Xu Yo, Wu ZK, Zhang X. Genotype-guided Warfarin Dosing in Patients with Mechanical Valves: a Randomized Controlled Trial. Ann Thorac Surg. 2018; 106(6): 1774-1781. 2. Xu Z, Fan J, Luo X, Zhang W-b, Ma J, Lin Y-b, Ma S-h, Chen X, Wang Z-p, Ou J-s, Zhang X. Anticoagulation regimens during pregnancy in patients with mechanical heart valves: a systematic review and meta-analysis. Can J Cardiol. 2016 Oct;32(10):1248.e1-1248.e9. 3. Xu Z, Wang ZP, Ou JS, Yin SL, Liu L, Zhang X. Is low anticoagulation intensity more beneficial for patients with bileaflet mechanical mitral valves? a meta-analysis. J Cardiovasc Surg (Torino). 2016; 57(1): 90-99. 4. Dong L, Shi YK, Xu JP, Zhang EY, Liu JC, Li YX, Ni YM, Yang Q, Han T, Fu B, Chen J, Ren L, Wei SL, Chen H, Liu KX, Yu FX, Liu JS, Xiao MD, Wu SM, Zhang KL, Huang HL, Jiang SL, Qiao CH, Wang CS, Xu ZY, Zhou XM, Wang DJ, Ni LX, Xiao YB, Jiang SL, Zhang GM, Liang GY, Yang SY, Bo P, Zhong QJ, Zhang JB, Zhang X, Zhu YB, Teng X, Zhu P, Huang F, Xiao YM, Cao GQ, Tian H, Xia LM, Lu FL, Liu YQ, Liu DX, Xu H, Yuan Y, Li M, Chang C, Wu XC, Xu Z, Guo P, Bai YJ, Xue WB, Jiang XY, Na ZH, Zeng QY, Cai H, Wang YL, Xiong R, Jin S, Zheng XM, Wu D. Multi-center registration and follow-up study of low-intensity anticoagulation therapy after heart valve surgery in China. Natl Med J China. 2016;96(19):1489-94. 5. Fan J, Luo X, Fan Y, Shen Y, Liu YQ, Zhang X, Xu Z* (Corresponding Author). Meta-analysis of two anticoagulation regimens during pregnancy after mechanical heart valve replacement. Chin J Pract Gynecol Obstet. 2014;30(12):962-968. 6. Hu R, Xu Z, Zhao LZ, Li JL, Wang XD, Zheng QS, Zhang X, Huang M. Study on the relationship between POR gene polymorphism and warfarin maintenance dose. Chin Pharmacol Bull. 2014;30(5):706-10. 7. Xu Z, Wang Z, Ou J, Xu Y, Yang S, Zhang X. Two Monitoring Methods of Oral Anticoagulant Therapy in Patients with Mechanical Heart Valve Prosthesis: A Meta-Analysis. J Thromb Thrombolysis. 2012; 33(1): 38-47. 8. Zhang X, Xu Z* (Corresponding Author), Tang BY, Chen YL, Wang ZP, Wu ZK, Yin SL. Meta-analysis of two monitoring methods for oral anticoagulant therapy. Chin J Thorac Cardiovasc Surg. 2010, 26(2):100-104. 9. Xu Z, Xu YQ, Xiong M, Zheng Y, Zhang X, Wang ZP, Wu ZK, Tang BY, Yin SL. Surgical treatment of mitral valve disease in elderly patients. J Sun Yat-sen Univ (Med Sci). 2009;30(4s):88-91. 10. Xu Z, Zhang X, Wang ZP, Wu ZK, Tang BY, Chen GX, Sun PW. Analysis of heart valve replacement in 99 patients with giant left ventricle. Guangdong Med J. 2007;28(8):1283-1285. 11. Zhang X, Xu Z, Xu YQ, Wang ZP, Wu ZK, Tang BY, Xiong M, Yao JP, Sun PW, Zhong FT. Surgical Intervention for Advanced Valvular Heart Diseases in 227 Cases. Chinese Medical Journal. 2005, 118(12): 1750-1752. **Books:** 1. Contributing Author, *Clinical Diagnosis and Treatment Plan* Series - Cardiothoracic Surgery Volume, Scientific and Technical Documentation Press, 2010 2. Contributing Author, *Essentials of Cardiothoracic Surgery* (2nd Edition), Tianjin Science and Technology Translation & Publishing Co., Ltd., 2010 **Other Major Achievements (e.g., Awards):** 2020 2nd Prize, Youth Excellent Paper Competition, 7th Annual Conference of Cardiovascular Surgery, Guangdong Medical Association 2016 3rd Prize, "Great Wall Young Physician Award", 27th Great Wall International Congress of Cardiology 2016 2nd Prize, Excellent Paper Competition, 18th Southern China International Congress of Cardiology 2012 3rd Prize, Excellent Educational Technology Research Achievement Award, Chinese Medical Association Education Technology Branch 2011 2nd Prize (Chinese Language Group), Young Faculty Teaching Competition, The First Affiliated Hospital, Sun Yat-sen University 2011 3rd Prize (Chinese Language Group), Young Faculty Teaching Competition, Zhongshan School of Medicine, Sun Yat-sen University 2011 Excellent Paper Award, Department of Cardiovascular Medicine, The First Affiliated Hospital, Sun Yat-sen University