**Main Education and Work Experience:** 1988–1993: Resident Physician, Department of General Surgery and Department of Cardiothoracic Surgery, The First Affiliated Hospital, Sun Yat-sen University. 1993–2001: Attending Physician, Department of Cardiothoracic Surgery, The First Affiliated Hospital, Sun Yat-sen University. 2001–2004: Associate Professor, Associate Chief Physician, Master's Supervisor, Department of Cardiothoracic Surgery, The First Affiliated Hospital, Sun Yat-sen University. May 1997 – Dec 2002: Clinical Fellow, Researcher, Department of Cardiac Surgery, Tampere University Hospital, Finland. Dec 2004 – Present: Researcher, Department of Cardiothoracic Surgery, The First Affiliated Hospital, Sun Yat-sen University. Dec 2005 – Present: Doctoral Supervisor, Department of Cardiac Surgery, The First Affiliated Hospital, Sun Yat-sen University. Dec 2007 – Present: Professor, Chief Physician, Department of Cardiac Surgery, The First Affiliated Hospital, Sun Yat-sen University. Dec 2011 – Present: Level II Professor, Level I Chief Physician, Department of Cardiac Surgery, The First Affiliated Hospital, Sun Yat-sen University. **Social Appointments:** Deputy Director, Key Laboratory of Assisted Circulation, Ministry of Health. Deputy Director, Department of Cardiovascular Medicine. Member, Expert Review Panel (Second Round Review), 12th and 13th National Natural Science Foundation of China. Editorial Board Member, 6th Editorial Committee, *Chinese Journal of Thoracic and Cardiovascular Surgery*. Editorial Board Member, *Chinese Journal of Clinical Medicine* (Engl). Standing Editorial Board Member, *Chinese Journal of Clinicians* (Electronic Edition). Editorial Board Member, *New Medicine*. Editorial Board Member, *Lingnan Journal of Cardiology*. Membership in the Scandinavian Society for Research in Cardiothoracic Surgery. Reviewer for *Circulation*, *The Annals of Thoracic Surgery*, *The American Journal of Cardiology*, *Chest*, and *Chinese Medical Journal*. Academic Committee Member, Cardiovascular Surgery Branch, Chinese Medical Doctor Association. Standing Committee Member, Cardiovascular Surgery Branch, Guangdong Medical Doctor Association. Committee Member, Guangdong Society of Cardiothoracic Surgery. Standing Committee Member, Guangzhou Youth Federation. **Publications:** A total of 74 papers have been published, including 26 papers as first author or corresponding author in SCI-indexed journals. **Papers Published in SCI Journals as First Author or Corresponding Author:** 1. Simvastatin attenuates pulmonary vascular remodeling by down-regulating matrix metalloproteinases-1,9 expressions in carotid artery-jugular vein shunt pulmonary hypertension model of rats. Eur. J. Cardiothorac. Surg 2012; (In press, Corresponding author). 2. Controlled Oxygen Reperfusion Protects the Lung against Early Ischemia- Reperfusion Injury in Cardiopulmonary Bypasses by Down-regulating High Mobility Group Box 1 Experimental Lung Research 2012 (In press, Corresponding author). 3. Mai Xiong, Zhong-Kai Wu. Fibrosis of pulmonary vascular remodeling in carotid artery-jugular vein shunt pulmonary artery hypertension model of rats. Eur. J. Cardiothorac. Surg 2012; 41(1): p. 162-166 (Corresponding author). 4. Gao X, Peng L, Zeng Q, Wu ZK. Relationship between autonomic nervous function and arrhythmias in patients with acute viral myocarditis. Cardiology. ,2009,113(1):66-71. (Corresponding author). 5. Wu ZK, Laurikka J, Vikman S, Nieminen R, Moilanen E, Tarkka MR. High Postoperative Interleukin-8 Levels Related to Atrial Fibrillation in Patients Undergoing Coronary Artery Bypass Surgery.World J Surg. 2008 Dec;32(12):2643-9. (Corresponding author). 6. Xu YQ, Wu ZK. Successfully surgical correction of total anomalous systemic venous drainage: two cases report. Heart Surgery Forum 2007;10(5):E415-7 (Corresponding author). 7. ZK Wu, S Vikman, J Laurikka, E Pehkonen, T Iivainen, HV Huikuri, and MR Tarkka. Nonlinear heart rate variability in CABG patients and the preconditioning effect. Eur. J. Cardiothorac. Surg 2005; 28: 109-13. (Corresponding author). 8. Zhang X, Wu ZK, Yao JP, et al. Aortopulmonary window—a case diagnosed by UFCT and the corrected method after transaortic patch closure with aortic narrowing. Chinese Medical Journal 2004;117：1750-1752。(Corresponding author) 9. Wu ZK, Iivainen T, Pehkonen E, et al. The antiarrhythmic effect of ischemic preconditioning in recent unstable angina patients undergoing coronary artery bypass grafting. World J Surg. 2004;28:74-9. 10. Wu ZK, Iivainen T, Pehkonen E, et al. Recent unstable angina and off-pump coronary artery bypass grafting is not related to postoperative atrial fibrillation。Scand Cardiovasc J. 2003;37:334-9. 11. Wu ZK, Iivainen T, Pehkonen E, et al. Fibrillation in patients subjected to coronary artery bypass grafting. J Thorac Cardiovasc Surg. 2003;126:1477-82. 12. Wu ZK, Iivainen T, Pehkonen E, et al. Arrhythmias in off-pump coronary artery bypass grafting patients and the antiarrhythmic effect of regional ischemic preconditioning. J Cardiothorac Vasc Anesth 2003;17:459-64. 13. Wu ZK, Laurikka J, Saraste A, et al. Cardiomyocyte apoptosis and ischemic preconditioning in open heart operations. Ann Thorac Surg 2003;76:528-534. 14. Wu ZK, Iivainen T, Pehkonen E, et al. Perioperaive and postoperative arrhythmia in 3-vessel coronary artery disease patients and antiarrhythmic effects of ischemic preconditioning. European J of Cardio-thoracic Surg 2003;23: 578-584. 15. Tarkka MR, Wu ZK. Ischemic preconditioning in cardiac surgery. Int J Angiology 2003;12:34-47. (Corresponding author) 16. Wu ZK, Iivainen T, Pehkonen E, et al. Ischemic preconditioning suppresses ventricular tachyarrhythmias after myocardial revascularization Circulation. 2002;106:3091-3096. 17. Wu ZK, Pehkonen E, Laurikka J, et al. Ischemic preconditioning protects right ventricular function in coronary artery bypass grafting patients experiencing angina within 48-72 hours. J Cardiovasc Surg 2002;43:319-26. 18. Wu ZK, Pehkonen E, Laurikka J, et al. The protective effects of preconditioning decline in aged patients undergoing coronary artery bypass grafting. J Thorac Cardiovasc Surg. 2001;122:972-8. 19. Wu ZK, Pehkonen E, Laurikka J, et al. Preceding unstable angina affects inflammatory response and haemodynamics after coronary artery bypass surgery. International J of Angiology 2001;10:80-84. 20. Wu ZK, Pehkonen E, Laurikka J, et al. Myocardial lactate production is not involved in the ischaemic preconditioning mechanism in CABG patients. J Cardiothorac Vasc Anesth. 2001;15:412-7. 21. Wu ZK, Tarkka MR, Eloranta J, et al. Effect of ischaemic preconditioning, cardiopulmonary bypass and myocardial ischaemic/reperfusion on free radicals generation in CABG patients. Cardiovasc Surg. 2001;9:362-8. 22. Wu ZK, Tarkka MR, Eloranta J, et al. Effect of ischemic preconditioning (IP) on myocardial protection in CABG patients: Can the free radicals act as a trigger for IP? Chest 2000; 119:1061-8. 23. Wu ZK, Pehkonen E, Laurikka J, et al. Protective effect of unstable angina in coronary artery bypass surgery. Scand Cardiovasc J 2000;34: 486-492. 24. Wu ZK, Tarkka MR, Pehkonen E, et al. Beneficial effects of ischemic preconditioning on right ventricular function after coronary artery bypass grafting. Ann Thorac Surg. 2000;70:1551-7. 25. Wu ZK, Sun PW, Zhang X, et al. Superiority of Mitral Valve Replacement with Preservation of Subvalvular Structure to Conventional Replacement in Severe Rheumatic Mitral Valve Disease. J Heart Valve Dis 2000;9:616-622. 26. Wu ZK, Tarkka MR, Pehkonen E, et al. Ischaemic Preconditioning has a Beneficial Effect on Left Ventricular Heamodynamic Function after a Coronary Artery Bypass Grafting Operation. Scand Cardiovasc J. 2000;34:247-253. **Papers Published in SCI Journals as Second Author, etc.:** 27. Liu Z