Leng Doctor Chief Physician

The First Affiliated Hospital, Sun Yat-sen University · Department of Cardiology I · Chief Physician

Cardiovascular specialist with MD and PhD from Sun Yat-sen University. Postdoctoral research at UT Southwestern on stem cell therapy for cardiovascular/cerebrovascular diseases. Published 12+ papers on warfarin pharmacogenomics, angiotensin-(1-7), and GPR68 in myocardial protection. Expertise in heart failure, vascular remodeling, and small molecule compounds for tissue regeneration.

Medical Expertise: Diagnosis and treatment of hypertension, coronary heart disease, heart failure, arrhythmias, valvular heart disease, and cardiomyopathy. Specializes in: ① Pharmacological management of cardiovascular diseases, including hypertension, coronary heart disease, heart failure, hyperlipidemia, valvular heart disease, cardiomyopathy, and metabolic syndrome. ② Comprehensive rehabilitation guidance for patients with cardiovascular diseases and those recovering from cardiac surgery, in

Leng Doctor
Doctor Photo
Basic Information

About Dr. Leng Doctor

Hospital
The First Affiliated Hospital, Sun Yat-sen University
Title
Chief Physician
Department
Department of Cardiology I
Years of Practice
28 years (1998 — present)
**Education and Professional Experience:** Enrolled at Sun Yat-sen University (formerly Sun Yat-sen Medical College) in 1989, graduated with a Master's degree in 1996 (seven-year program). Master's thesis: Study on heart rate variability in hypertensive patients. Received a Doctorate in Cardiovascular Medicine in 2004. Doctoral thesis: Study on leptin in heart failure. Won the First Prize in the English Teaching Category of the First Young and Middle-aged Teacher Teaching Competition at Sun Yat-sen University in 2006. Advanced training in cardiovascular ultrasound at Prince of Wales Hospital in Hong Kong in 2008. Postdoctoral research at the University of Texas Southwestern Medical Center from 2011 to 2013, focusing on stem cell therapy for cardiovascular and cerebrovascular diseases. Postdoctoral project: Development of small molecule compounds to promote myocardial and brain cell regeneration, and the protective role of the novel coronary heart disease therapeutic target G protein-coupled receptor (GPR68) in myocardial ischemia and hypoxia. **Publications:** 1. Genetic polymorphisms of VKORC1, CYP2C9, CYP4F2 in Bai, Tibetan Chinese. Pharmazie, 2012, 67, 69-73. 2. Angiotensin-(1-7) reduced postangioplasty vascular fibrosis in abdominal aorta of rabbits. Chinese Journal of Cardiology, 2010, 38 (6): 531-538. 3. Chronic angiotensin-(1-7) administration improves vascular remodeling after angioplasty through the regulation of the TGF-β/Smad signaling pathway in rabbits. Biochemical and Biophysical Research Communications (BBRC), 2009, 389: 138-144. 4. CYP4F2 rs2108622: a minor significant genetic factor of warfarin dose in Han Chinese patients with mechanical heart valve replacement. Br J Clin Pharmacol. 2010, 70(2): 234-240. 5. Coupling hippocampal neurogenesis to brain pH through proneurogenic small molecules that regulate proton sensing G protein-coupled receptors. ACS Chem Neurosci. 2012 Jul 18; 3(7): 557-68. 6. Effect of NR112 gene polymorphisms on individual differences in warfarin maintenance dose. Chinese Journal of Pharmacology and Toxicology, 2012, 26(2): 219-224. 7. Mechanism and common issues of enhanced external counterpulsation. New Medicine, 2008, 39(3): 144-147. 8. Protective effect of angiotensin-(1-7) on vascular endothelial function and integrity in rabbit acute myocardial infarction reperfusion. Journal of Sun Yat-sen University (Medical Sciences), 2008, 29(3): 278-282. 9. Effect of low-dose simvastatin on vascular endothelial function in elderly patients with coronary heart disease. New Medicine, 2008, 39(1): 18-20. 10. Study on changes in cerebrospinal fluid and serum leptin in rats with heart failure. Journal of Sun Yat-sen University (Medical Sciences), 2007, 28(6): 654-657. 11. Changes in leptin in patients with chronic heart failure and its impact on prognostic assessment. Chinese Journal of Arteriosclerosis, 2007, 11(5): 457-460. 12. Summary of the 2006 First International Symposium on External Counterpulsation and China's External Counterpulsation Application and Development Strategy Summit Forum. Chinese Journal of Cardiology, 2006, Issue 10. **Monographs:** Deputy Editor-in-Chief of *Differential Diagnosis of Internal Medicine Symptoms*. Contributing author to *Clinical Cardiac Stress Testing*, *Advanced Pathophysiology* (textbook), *Hypertension*, and other monographs.
Schedule

Dr. Leng Doctor — Outpatient Schedule

Weekly clinic, including specialist and surgery days. Book 3-7 days in advance.

Clinic: The First Affiliated Hospital, Sun Yat-sen University · Department of Cardiology I
On Duty
Off Duty
Period Morning
08:00-12:00
Afternoon
14:00-17:30
Evening
18:30-20:30
Mon Off Duty Off Duty Off Duty
Tue On Duty
09:00 - 12:00
Off Duty Off Duty
Wed Off Duty Off Duty Off Duty
Thu On Duty
09:00 - 12:00
Off Duty Off Duty
Fri Off Duty Off Duty Off Duty
Sat Off Duty Off Duty Off Duty
Sun Off Duty Off Duty Off Duty
Note: Actual clinic hours are subject to the hospital's daily notice. Please call the Dovecure 24h hotline 400-888-0000 to confirm before booking.

Rationale for Precision

Senior Medical Advisory Team — With an average of over five years of clinical experience, the team has supported over 1,000 families in accessing coordinated, high-quality medical care in China.

Book your dedicated advisor now

Senior Medical Advisory Team — With an average of over five years of clinical experience, the team has supported over 1,000 families in accessing coordinated, high-quality medical care in China.

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