**Main Education and Work Experience:**
Graduated with a bachelor's degree from Sun Yat-sen University of Medical Sciences in 1986, and obtained a master's and doctoral degree in medicine from the same institution. From 2003 to 2005, conducted postdoctoral research at the Renal Division of Boston Medical Center, Boston University, USA. Has worked in the Department of Nephrology at the First Affiliated Hospital of Sun Yat-sen University for over 20 years, accumulating extensive clinical experience in diagnosis and treatment.
**Research Grants:**
Principal investigator of 4 projects funded by the Guangdong Provincial Natural Science Foundation, 2 projects funded by the Guangdong Provincial Science and Technology Plan, 1 project funded by the Guangzhou Municipal Science and Technology Bureau, and a major participant in 2 projects funded by the National Natural Science Foundation of China. Details are as follows:
(1) Protective effect of GSK3β inhibitors on renal ischemia/reperfusion injury
2006 Guangdong Provincial Natural Science Foundation – Principal Investigator
(2) Role of glycogen synthase kinase 3 (GSK3) in renal interstitial fibrosis
2006 Guangdong Provincial Science and Technology Plan – Principal Investigator
(3) Epidemiological survey and gene polymorphism analysis of first-degree relatives of chronic kidney disease patients
2009 Guangdong Provincial Science and Technology Plan – Principal Investigator
(4) Role of the microRNA200 family in BMP-7 reversing peritoneal mesothelial cell mesenchymal transition
2010 Guangdong Provincial Natural Science Foundation – Principal Investigator
(5) Exome sequencing analysis to identify susceptibility genes for familial IgA nephropathy
2011 Guangdong Provincial Natural Science Foundation – Principal Investigator
(6) Effects and mechanisms of molecular chaperone HSP70 on EMT and renal interstitial fibrosis
2006 National Natural Science Foundation of China – Major Participant
(7) Effects of HSP72 on (myo)fibroblast activation, proliferation, and function during renal fibrosis
2010 National Natural Science Foundation of China – Major Participant
**Professional Affiliations:**
Member of the Guangdong Provincial Society of Nephrology
**Publications:**
To date, has published 50 papers in major domestic and international journals, including 11 SCI-indexed articles, with 4 as first author/co-first author. The following are major publications from the past two years:
1. Li ZJ (first author), An X, Mao HP, Wei X, Chen JH, Yang X, Zhou SF, Li ZB, Yu XQ. Effect of depression on malnutrition-inflammation complex syndrome in patients with continuous ambulatory peritoneal dialysis. *Int Urol Nephrol*. 2011 Sep;43(3):875-82.
2. Xin An, Hai-Ping Mao, Xin Wei, Jie-Hui Chen, Xiao Yang, Zhi-Bin Li, Xue-Qing Yu, Zhi-Jian Li (corresponding author). Elevated neutrophil to lymphocyte ratio predicts overall and cardiovascular mortality in maintenance peritoneal dialysis patients. *Int Urol Nephrol*. 2012 Jan;(Epub ahead of print).
3. Wei X, Li Z (co-first author), Chen W, Mao H, Li Z, Dong X, Tan J, Ling L, Chen A, Guo N, Yu X. Prevalence and risk factors of chronic kidney disease in first-degree relatives of chronic kidney disease patients in Southern China. *Nephrology (Carlton)*. 2012 Feb;17(2):123-30.
4. Yu XQ, Li M, Zhang H, Low HQ, Wei X, Wang JQ, Sun LD, Sim KS, Li Y, Foo JN, Wang W, Li ZJ, Yin XY, Tang XQ, Fan L, Chen J, Li RS, Wan JX, Liu ZS, Lou TQ, Zhu L, Huang XJ, Zhang XJ, Liu ZH, Liu JJ. A genome-wide association study in Han Chinese identifies multiple susceptibility loci for IgA nephropathy. *Nat Genet*. 2011; 10:1038-1047.
**Monographs:**
Contributed to the writing of 5 academic monographs, including *Clinical Diagnosis and Treatment Protocols for Renal Diseases*.
**Other Major Achievements (e.g., Awards):**
Participated in winning the National Science and Technology Progress Award (Second Class), the Chinese Medical Science and Technology Award (Second Class), the Guangdong Provincial Science and Technology Award (Second Class), and the Guangzhou Municipal Science and Technology Bureau Achievement Award.