**Main Education and Work Experience:**
**Main Education:**
1980.9~1986.7 Bachelor of Medicine, Department of Medicine, Zhongshan Medical University
1998.9~2003.7 Master of Medicine (Equivalent Academic Level), Sun Yat-sen University
**Work Experience:**
1986.7~1992.12 Resident Physician, Teaching Assistant, Department of Internal Medicine, First Affiliated Hospital of Zhongshan Medical University
1992.12~1999.12 Attending Physician, Lecturer, Department of Respiratory Medicine, First Affiliated Hospital of Zhongshan Medical University
1999.12~2006.12 Associate Chief Physician, Department of Respiratory Medicine / Medical ICU, First Affiliated Hospital of Sun Yat-sen University
2006.12~Present Chief Physician / Professor, Department of Respiratory Medicine / Medical ICU, First Affiliated Hospital of Sun Yat-sen University
2005.9~2009.10 Director of MICU, Deputy Director of Department of Respiratory Medicine, First Affiliated Hospital of Sun Yat-sen University
2009.10~2016.11 Deputy Director of Department of Critical Care Medicine, Director of MICU, First Affiliated Hospital of Sun Yat-sen University
2016.11~Present Director of MICU, First Affiliated Hospital of Sun Yat-sen University
**Social Appointments:**
Vice Chairman, Guangdong Branch, Chinese Medical Association Tuberculosis Society
Vice Chairman, Guangdong Provincial Committee of Integrated Traditional Chinese and Western Medicine Critical Care Medicine
Vice Chairman, ICU Committee, Guangdong Health Management Association
Member, Critical Care Medicine Group, Respiratory Society, Chinese Medical Association
Member, ICU Group, Respiratory Physician Branch, Chinese Medical Doctor Association
Standing Committee Member, Anti-Infective Drug Expert Committee, Guangdong Pharmaceutical Association
Member, Critical Care Medicine Branch, Guangdong Medical Association
Member, Critical Care Medicine Branch, Guangdong Medical Doctor Association
Member, Infection Group, Respiratory Society, Guangdong Medical Association
Member, Respiratory Disease Equipment Professional Committee, China Medical Equipment Association
**Publications:** Over 80 published papers (including SCI).
1. Ghrelin Attenuates Sepsis-Associated Acute Lung Injury Oxidative Stress in Rats. Inflammation. 2015. Vol.38(2):683-690
2. Local and Systemic Oxidative Stress Status in Chronic Obstructive Pulmonary Disease Patients. Can Respir J. 2013; Vol.20(1):35-41
3. Role of TNF-α and sTNF-R55 and sTNF-R75 in Inflammation of Acute Exacerbations of Chronic Obstructive Pulmonary Disease. Respiration. 2009;78(4):399-403
4. Ghrelin Protects Alveolar Macrophages Against Lipopolysaccharide-Induced Apoptosis Through Growth Hormone Secretagogue Receptor 1a-Dependent c-Jun N-Terminal Kinase and Wnt/β-Catenin Signaling and Suppresses Lung Inflammation. Endocrinology. 2015 Jan;156(1):196-210.
5. Effects of ghrelin on apoptosis in human neutrophil in vitro. International Journal of Molecular Medicine. 2016, 38(3):794-802.
6. Ghrelin ameliorates the human alveolar epithelial A549 cell apoptosis induced by Lipopolysaccharide. Biochemical and Biophysical Research Communications. 2016, 474(1):83-90
7. Clinical value of soluble urokinase-type plasminogen activator receptor in the diagnosis, prognosis, and therapeutic guidance of sepsis. American Journal of Emergency Medicine. 2015, 34(3):375-80.
8. Effects of Ghrelin on Pulmonary Nitrosative Stress in Septic Rats. Journal of Sun Yat-sen University (Medical Sciences), 2013, Vol.34(2):220-224.
9. Effects of Ghrelin on iNOS Expression in Alveolar Macrophages and Lung Tissue of Rats with Sepsis-Associated Lung Injury. Chinese Journal of Pathophysiology, 2013, 29(5):895-899.
10. Ghrelin Inhibits LPS-Induced Apoptosis of Alveolar Macrophages via the JNK Signaling Pathway. Journal of Sun Yat-sen University (Medical Sciences), 2015, 36(2):181-188
11. Effects of Ghrelin on LPS-Induced Apoptosis of Alveolar Epithelial Cells via the AKT/ERK Signaling Pathway. Chinese Journal of Immunology, 2017; Vol.33(8):1129-1134.
12. Analysis of Influencing Factors of Occult Renal Failure in Patients with Chronic Obstructive Pulmonary Disease. Chinese Journal of Gerontology, 2016, Vol.36(8):1928-1930.
13. Diagnostic Value of Soluble Urokinase-Type Plasminogen Activator Receptor in Sepsis. Chinese Journal of Emergency Medicine. 2015; Vol.24(7):772-778.
14. Changes in Plasma ADAMTS-13 and Inflammatory Factors in Patients with Non-Acute Pulmonary Thromboembolism. Journal of Sun Yat-sen University (Medical Sciences), 2015, Vol.36(1):131-134
15. Can New Treatments for ARDS Benefit Patients? Chinese Journal of Emergency Medicine, 2017, Vol.26(3):251-254
16. Pathogenesis and Management Strategies for Ventilator-Associated Acid-Base Imbalance. Chinese Journal of Tuberculosis and Respiratory Diseases, 2014, Vol.37(5):398-400.
**Monographs:** Editor-in-chief of 1 book ("Respiratory Therapy and Clinical Application"), participated in the compilation of over 10 books.
**Grants:** Received over 10 projects from the National Natural Science Foundation of China and provincial/ministerial level funds.
**Other Major Work Achievements (e.g., Awards):**
1. Third Prize of Guangdong Provincial Science and Technology Award (1 item).
2. Hospital-level Medical Ethics Model.
3. First-Class Merit for Combating Atypical Pneumonia in Guangdong Province; Guangdong Province "March 8th" Red-Banner Holder.