**Education and Professional Experience:** 1982.9 – 1988.6: Bachelor's Degree, Department of Clinical Medicine, Beijing Medical University 1988.7 – 1991.8: Resident Physician, Department of Surgery, Second Affiliated Hospital of Jiangxi Medical College 1991.9 – 1996.6: Graduate Studies, Doctor of Medicine (Ph.D.), Sun Yat-sen University of Medical Sciences 1996.7 – 1999.11: Attending Physician, Department of Orthopedics, The First Affiliated Hospital, Sun Yat-sen University 1999.12 – 2011.11: Associate Chief Physician, Department of Spine Surgery, The First Affiliated Hospital, Sun Yat-sen University 2011.12 – Present: Chief Physician, Department of Spine Surgery, The First Affiliated Hospital, Sun Yat-sen University 2014.12 – Present: Professor, Department of Spine Surgery, The First Affiliated Hospital, Sun Yat-sen University Current Positions: Deputy Director, Department of Orthopedics-Microsurgery; Director, Department of Spine Surgery, The First Affiliated Hospital, Sun Yat-sen University **Professional Affiliations:** 1. Expert for the Fifth Guangdong Provincial Health Care Consultation, Health Care Committee of the CPC Guangdong Provincial Committee 2. Vice Chairman, Spine Surgery Branch, Guangdong Medical Association 3. Vice Chairman, Spine Surgery Branch, Guangdong Medical Doctor Association 4. Vice Chairman, Spine Surgery Branch, Guangdong Association of Integrative Medicine 5. Member, Spinal Tumor Group, Professional Committee on Spinal Cord Injury and Repair, Chinese Association of Rehabilitation Medicine **Awards:** 1. Project: "Research on Novel Therapies for Spinal Cord Injury Repair and Application of Intraoperative Electrophysiological Monitoring" – Awarded the Second Prize of the 2018 Guangdong Provincial Science and Technology Progress Award **Publications (Selected Articles):** 1. Analysis of the efficacy of surgical treatment for thoracic spinal stenosis; Chinese Journal of Spine and Spinal Cord, 2010, Issue 08 2. Investigation of the therapeutic time window of recombinant human erythropoietin for acute spinal cord injury in rats; Chinese Journal of Spine and Spinal Cord, 2010, Vol. 20, Issue 9 3. Surgical treatment of cervical spine tumors in children; Journal of Sun Yat-sen University (Medical Sciences), 2009, S2 Issue 4. Clinical value of the Tokuhashi score, revised Tokuhashi score, and Tomita surgical score in predicting the prognosis of patients with epidural spinal metastases; Chinese Journal of Oncology, 2010, Issue 11 5. Two-dimensional electrophoresis of peripheral blood CD4+ T lymphocytes in ankylosing spondylitis; Anatomy Research, 2011, Issue 04 **Monographs:** 1. Craniospinal Traction Technique for Spinal Deformities. 2. Handbook of Surgery **Representative Publications (Last 5 Years):** 1. Li, Xiang (#); Peng, Zhiming (#); Long, Lingli (#); Wan, Yong (*); Tuo, Ying; Wang, Liqin; Zhao, Xiaoyang; Wang, Le. Wnt4-modified NSC transplantation promotes functional recovery after spinal cord injury. *FASEB J*, 2020 Jan 3; 34(1): 82-94. (SCIE, IF: 5.31) 2. Li, Xiang (#); Peng, Zhiming (#); Long, Lingli (#); Wang, Le (*); Wan, Yong (*); Lu, Xiaofang; Zhu, Kai; Tuo, Ying; Chen, Ningning; Zhao, Xiaoyang. Transplantation of Wnt5a-modified NSC promotes tissue repair and locomotor functional recovery after Spinal Cord Injury. *Exp Mol Med*, 2020 Dec 14, online. (SCIE, IF: 5.41) 3. Chen, Ningning (#); Zhou, Pengxiang (#); Liu, Xizhe (#); Wan, Yong (*); Liu, Shaoyu; Wei, Fuxin; Li, Jiachun. Overexpression of Rictor in the injured spinal cord promotes functional recovery in a rat model of spinal cord injury. *FASEB J*, 2020 May 17; 34(5): 6984-6998. (SCIE, IF: 5.31) 4. Zhang Wenwu, Chen Jiewen, Guo Weimin, Kong Ganggang, Wang Le, Cheng Xing, Zeng Xiaolin, Wan Yong (*), Li Xiang (*). WKYMVm/FPR2 Alleviates spinal cord injury by attenuating the inflammatory response of microglia. *Mediator of Inflammation*, 2022, 4408099. (IF: 4.53) 5. Chen Jiewen, Zeng Xiaolin, Wang Le, Zhang Wenwu, Li Gang, Cheng Xing, Su Peiqiang, Wan Yong (*), Li Xiang (*). Mutual regulation of microglia and astrocytes after Gas inhibits spinal cord injury. *Neural Regeneration Research*, 2025 Feb 1; 20(2): 557-573. (IF: 6.10) 6. Pan Baigi, Wu Xiaoyu, Zeng Xiaolin, Chen Jiewen, Zhang Wenwu, Cheng Xing, Wan Yong (*), Li Xiang (*). Transplantation of Wnt4-modified neural stem cells mediate M2 polarization to improve inflammatory micro-environment of spinal cord injury. *Cell Prolif*, 2023 Feb 6; e13415. (IF: 8.78)