**Education:** 1997.9-2002.7 Sun Yat-sen University, Clinical Medicine, Seven-year Master's Program (Undergraduate Phase) 2002.9-2004.7 Sun Yat-sen University, Surgery, Seven-year Master's Program 2004.9-2007.7 The First Affiliated Hospital, Sun Yat-sen University, Surgery, Doctorate 2017.9-2019.2 University of Massachusetts / Massachusetts General Hospital, Visiting Scholar **Professional Experience:** 2007/07-2010/11 Department of Hepatobiliary Surgery, The First Affiliated Hospital, Sun Yat-sen University, Resident Physician 2010/12-2013/11 Department of Hepatobiliary Surgery, The First Affiliated Hospital, Sun Yat-sen University, Attending Physician, Lecturer 2013/12-2019/11 Department of Hepatobiliary (Biliary-Pancreatic) Surgery, The First Affiliated Hospital, Sun Yat-sen University, Associate Professor, Associate Chief Physician 2014/6-2014/12 The First People's Hospital of Fangchenggang, Guangxi (Partner Assistance), Dean's Assistant, Deputy Director of General Surgery 2019/12-Present Department of Biliary-Pancreatic Surgery, The First Affiliated Hospital, Sun Yat-sen University, Chief Physician **Professional Affiliations:** 2018 Recipient of Hurun Report - Ping'an China Good Doctor Award Member, Youth Committee, Biliary Surgery Branch, Chinese Medical Doctor Association Member, Youth Committee, Pancreatic Cancer Professional Committee, Chinese Anti-Cancer Association Member, Youth Committee, Enhanced Recovery After Surgery Professional Committee, Chinese Research Hospital Association Member, Biliary Tract Group, Hepatobiliary and Pancreatic Surgery Branch, Guangdong Medical Association Member, Spleen and Portal Hypertension Group, Hepatobiliary and Pancreatic Surgery Branch, Guangdong Medical Association Member, Pancreatic Disease Group, Surgery Branch, Guangdong Medical Association Standing Committee Member, Youth Committee, Biliary Tract Tumor Professional Committee, Guangdong Anti-Cancer Association Standing Committee Member, Portal Hypertension Management Branch, Guangdong Medical Industry Association Standing Committee Member, Pancreatic Disease Professional Committee, Guangdong Health Management Association Editorial Board Member, Chinese Journal of Hepatic Surgery (Electronic Edition). **Publications:** **(I) First/Corresponding Author** 1. Chen D, Zhao P, Li SQ, Xiao WK, Yin XY, Peng BG, Liang LJ. Prognostic impact of pERK in advanced hepatocellular carcinoma patients treated with sorafenib. Eur J Surg Oncol, 2013, 39(9):974-980. (IF=3.379) 2. Chen W, Xiao W, Zhang K, Yin X, Lai J, Chen D. Activation of c-Jun predicts a poor response to sorafenib in hepatocellular carcinoma: Preliminary Clinical Evidence. Sci Rep, 2016, Mar 11; 6:22976. Doi:10.1038/srep22976. (IF=4.011, corresponding author) **(II) Co-first Author** 3. Wei-Kai Xiao, Dong Chen, Shao-Qiang Li*, Shun-Jun Fu, Bao-gang Peng, Li-jian Liang. Prognostic significance of neutrophil-lymphocyte ratio in hepatocellular carcinoma: a meta-analysis. BMC Cancer, doi:10.1186/1471-14-117, 2014 (IF=2.933, co-author) 4. Xiao WK, Chen D, Hu AB, Peng BG, Guo YZ, Fu SJ, Liang LJ, Li SQ*. Radiofrequency-assisted versus clamp-crush liver resection: a systematic review and meta-analysis. J Surg Res, 2014, 187(2):471-83. (IF=1.872, co-author) 5. Hu ZC, Chen D, Guo D, Liang YY, Zhang J, Zhu JY, Tang B. Randomized clinical trial of autologous skin cell suspension combined with skin grafting for chronic wounds. Br J Surg, 2015, 102(2):e117-23. Doi:10.1002/bjs.9688. (IF=5.572, co-author) **(III) Second Author** 6. Wang XY, Chen D, Zhang XS, Chen ZF, Hu AB. Value of (18) F-FDG-PET/CT in the detection of recurrent hepatocellular carcinoma after hepatectomy or radiofrequency ablation: A comparative study with contrast-enhanced ultrasound. J.Dig.Dis.2013,14:433-438. (IF=1.689) **(IV) Third Author and Beyond** 7. Zhou Lu-yao, Xie Xiao-yan, Chen Dong, Lv Ming-de. Contrast-enhanced ultrasound in detection and follow-up of pancreaticoduodenal artery pseudoaneurysm: a case report. Chin Med J, 2011, 124(7):2792-2794. (IF=1.555) 8. Wei-Kai Xiao, Chao-Ying Qi, Dong Chen, Shao-Qiang Li, Shun-Jun Fu, Bao-Gang Peng, & Li-Jian Liang. (2014). Prognostic significance of glypican-3 in hepatocellular carcinoma: a meta-analysis. BMC Cancer, 14(1), 1–20. doi: 10.1186/1471-2407-14-104. (IF=2.933) 9. Zhang J, Hu Z-C, Chen D, Guo D, Zhu J-Y, Tang B. Effectiveness and Safety of Negative-Pressure Wound Therapy for Diabetic Foot Ulcers: A Meta-Analysis. Plast.Reconstr.Surg.2014.07, 134(1):141-151. (IF=3.946) 10. Yang, A., Xiao, W., Chen, D., Wei, X., Huang, S., Lin, Y., … He, X. (n.d.). The power of tumor sizes in predicting the survival of solitary hepatocellular carcinoma patients. CANCER MED, 2018.12, 7(12), 6040–6050. (IF=3.357) 11. Peng S, Wang Y, Peng H, Chen D, Shen S, Peng B, Chen M, Lencioni R, Kuang M. Autocrine vascular endothelial growth factor signaling promotes cell proliferation and modulates sorafenib treatment efficacy in hepatocellular carcinoma. Hepatology. 2014, 60(4):1264-1277. DOI:10.1002/hep.27236. (IF=14.971) 12. Zhou, L., Jiang, H., Shan, Q., Chen, D., Lin, X., Liu, B., & Xie, X. (2017). Liver stiffness measurements with supersonic shear wave elastography in the diagnosis of biliary atresia: a comparative study with grey-scale US. Eur. Radiol, 2017.08, (8), 3474. (IF=3.962) 13. Shao-qiang Li, Li-jian Liang, Yun-peng Hua, Bao-gang Peng, Dong Chen, Shun-jun Fu. Bilateral liver resection for bilateral intrahepatic stones. WJG. 2009, 15(29):3660-3663. (IF=3.411) 14. Zhou Qi, Huang Tao, Wang Ya-feng, Zhang Kun-song, Chen Dong, Peng Bao-gang. Identification of Max binding protein as a novel binding protein of Nck1 and Characterization of its role in inhibiting human liver cancer SK-HEP-a cells. Chin Med J, 2012;125(18):3336-3339. (IF=1.555) 15. Guo, Y., Wang, J., Li, H., Liu, W., Chen, D., Zhao, K., … Chen, G. (2015). Mediator subunit 23 overexpression as a novel target for suppressing proliferation and tumorigenesis in hepatocellular carcinoma. J. Gastroenterol. Hepatol, 2015.06, (6), 1094. (IF=3.632) 16. Zhang Z, Huang S, Wang H, Wu J, Chen D, Peng B, Zhou Q. High expression of hexokinase domain containing 1 is associated with poor prognosis and aggressive phenotype in hepatocarcinoma. Biochem Biophys Res Commun, 2016, 474(4):673-679. (IF=2.705) 17. YANGDI WANG,* XIAOYAN XIE,* QINGHUA CAO, WENXUAN XIE, DONG CHEN, XIAOER ZHANG,* YU GUO, LUYAO ZHOU*. Quantitative contrast-enhanced ultrasound by sonazoid in the early diagnosis of biliary atresia: an experimental study of rats with bile duct ligation. Ultrasound in medicine and biology, 2019;45(10):2767-2776. **Books/Monographs:** 1. Chen Dong, Lu Zhenhai (Editors-in-Chief). People's Medical Publishing House, *Difficult Internal Medicine Cases: Oncology Volume*, November 2011, 1st Edition, 1st Printing, ISBN: 978-7-117-14623-4. Total words: 376,000. Words contributed: 13,000. 2. Tang Bing, Chen Dong, Zhu Jiayuan, Liao Weiming (Editors-in-Chief). Scientific and Technical Documentation Press, *Surgery Concise Notes and Postgraduate Entrance Exam Guide*, June 2013, 1