**Education and Professional Experience:**
1997.09-2003.06 Shandong University, School of Clinical Medicine Bachelor's Degree
2003.09-2008.12 The First Affiliated Hospital, Sun Yat-sen University, Department of Musculoskeletal Oncology Doctorate Degree
2007.09-2008.09 MD Anderson Cancer Center, USA Postdoctoral Fellow
2009.07-2011.12 The First Affiliated Hospital, Sun Yat-sen University, Department of Musculoskeletal Oncology Resident Physician
2011.12-2013.12 The First Affiliated Hospital, Sun Yat-sen University, Department of Musculoskeletal Oncology Attending Physician
2013.12-2019.12 The First Affiliated Hospital, Sun Yat-sen University, Department of Musculoskeletal Oncology Associate Chief Physician
2020.01-Present The First Affiliated Hospital, Sun Yat-sen University, Department of Musculoskeletal Oncology Chief Physician
**Professional Affiliations:**
Member, Sarcoma Committee, Chinese Anti-Cancer Association
Deputy Head, Basic Research Group, Sarcoma Committee, Chinese Anti-Cancer Association
Member, Chemoradiotherapy Group, Sarcoma Committee, Chinese Anti-Cancer Association
Member, Soft Tissue Sarcoma Group, Sarcoma Committee, Chinese Anti-Cancer Association
Member, Limb Working Committee, Bone Tumor Group, Orthopedics Branch, Chinese Medical Association
Member, Bone and Soft Tissue Tumor Committee, China Medical Education Association
Member, Oncology Branch, Guangdong Medical Association
Special Reviewer, *Chinese Journal of Joint Surgery (Electronic Edition)*
Special Reviewer, *The Journal of Practical Medicine*
**Publications:**
Authored over 40 SCI-indexed articles, including 16 as first/co-first/corresponding author, with a highest single-article impact factor of 16.806.
**SCI Articles as First/Co-first/Corresponding Author:**
1. Lu B, Zou C* (co-first), Yang M, He Y, He J, Zhang C, Chen S, Yu J, Liu KY, Cao Q, Zhao W. Pharmacological Inhibition of Core Regulatory Circuitry Liquid-liquid Phase Separation Suppresses Metastasis and Chemoresistance in Osteosarcoma. *Adv Sci (Weinh)*. 2021 Aug 25:e2101895. doi: 10.1002/advs.202101895.
2. Wa Q, Zou C* (co-first), Lin Z, Huang S, Peng X, Yang C, Ren D, Xu D, Guo Y, Liao Z, Wang B, Hu H, Huang S, He P. Ectopic Expression of miR-532-3p Suppresses Bone Metastasis of Prostate Cancer Cells via Inactivating NF-κB Signaling. *Mol Ther Oncolytics*. 2020 Apr 7;17:267-277. doi: 10.1016/j.omto.2020.0024. eCollection 2020 Jun 26.
3. Li X, Wang L, Wang L, Yu J, Lu G, Zhao W, Miao C, Zou C# (co-corresponding), Wu J#. Overcoming therapeutic failure in osteosarcoma via Apatinib-encapsulated hydrophobic poly(ester amide) nanoparticles. *Biomater Sci*. 2020 Oct 1. doi: 10.1039/d0bm01296c.
4. Zhang J*, Liu W*, Zou C* (co-first), Zhao Z, Lai Y, Shi Z, Xie X, Huang G, Wang Y, Zhang X, Fan Z, Su Q, Yin J, Shen J. Targeting Super-Enhancer-Associated Oncogenes in Osteosarcoma with THZ2, a Covalent CDK7 Inhibitor. *Clin Cancer Res*. 2020 Jun 1;26(11):2681-2692.
5. Zou C*, Zhao Z*, Lin T, Huang Y, Xie X, Yin J, Huang G, Wang B, Shen J. Long-term outcomes of limb salvage treatment with custom-made extendible endoprosthesis for bone sarcoma around the knee in children. *J Orthop Surg Res*. 2020 Jan 16;15(1):14. doi: 10.1186/s13018-019-1534-x.
6. Lu B, He Y, He J, Wang L, Liu Z, Yang J, Gao Z, Lu G, Zou C, Zhao W. Epigenetic Profiling Identifies LIF as a Super-enhancer-Controlled Regulator of Stem Cell-like Properties in Osteosarcoma. *Mol Cancer Res*. 2020 Jan;18(1):57-67. doi: 10.1158/1541-7786.MCR-19-0470. Epub 2019 Oct 15.
7. Wa Q, Huang S, Pan J, Tang Y, He S, Fu X, Peng X, Chen X, Yang C, Ren D, Huang Y, Liao Z, Huang S, Zou C. miR-204-5p Represses Bone Metastasis via Inactivating NF-κB Signaling in Prostate Cancer. *Mol Ther Nucleic Acids*. 2019 Dec 6;18:567-579. Epub 2019 Sep 18.
8. Zou C#, Lin T#, Wang B, Zhao Z, Li B, Xie X, Huang G, Yin J, Shen J. Managements of giant cell tumor within the distal radius: A retrospective study of 58 cases from a single center. *J Bone Oncol*. 2018 Dec 14;14:100211. doi: 10.1016/j.jbo.2018.100211. eCollection 2019 Feb.
9. Wang B, Zou C (co-first), Hu X, Tu J, Yao H, Yin J, Huang G, Xie X, Shen J. Reconstruction with a novel combined hemipelvic endoprosthesis after resection of periacetabular tumors involving the sacroiliac joint: a report of 25 consecutive cases. *BMC Cancer*. 2019 Aug 30;19(1):861.
10. Shuai Huang, Changye Zou (co-first), Yubo Tang, Qingde Wa, Xinsheng Peng, Xiao Chen, Chunxiao Yang, Dong Ren, Yan Huang, Zhuangwen Liao, Sheng Huang, Xuenong Zou, Jincheng Pan. miR-582-3p and miR-582-5p Suppress Prostate Cancer Metastasis to Bone by Repressing TGF-β Signaling. *Mol Ther Nucleic Acids*. 2019 Jun 7; 16: 91–104.
11. Liu W#, Zhang J#, Zou C# (co-first author), Xie X, Wang Y, Wang B, Zhao Z, Tu J, Wang X, Li H, Shen J*, Yin J*. Microarray Expression Profile and Functional Analysis of Circular RNAs in Osteosarcoma. *Cell Physiol Biochem*. 2017;43(3):969-985.
12. Wu J, Sun H1, Li J, Guo Y, Zhang K, Lang C, Zou C (co-corresponding), Ma H. Increased survival of patients aged 0-29 years with osteosarcoma: A period analysis, 1984-2013. *Cancer Med*. 2018 Jul 10. 2018 Aug;7(8):3652-3661.
13. Zou C#, Shen J#, Tang Q, Yang Z, Yin J, Li Z, Xie X, Huang G, Lev D, Wang J*. Cancer-testis antigens expression in osteosarcoma identified by gene microarray correlate with poor prognosis. *CANCER*. 2012 Apr 1;118(7):1845-55.
14. Zou C#, Smith KD#, Liu J, Lahat G, Myers S, Wang WL, Zhang W, McCutcheon IE, Slopis JM, Lazar AJ, Pollock RE*, Lev D*. Clinical, pathological and molecular variables predictive of malignant peripheral nerve sheath tumor (MPNST) outcome. *Ann Surg*. 2009 Jun;249(6):1014-22.
15. Zou CY#, Smith KD#, Zhu QS, Liu J, McCutcheon IE, Slopis JM, Meric-Bernstam F, Peng Z, Bornmann WG, Mills GB, Lazar AJ, Pollock RE, Lev D*. Dual targeting of AKT and mTOR: a potential therapeutic approach for malignant peripheral nerve sheath tumor. *Mol Cancer Ther*. 2009 May;8(5):1157-68.
16. Zou CY, Wang J, Shen JN*, Huang G, Jin S, Yin JQ, Guo QC, Li HM, Luo L, Zhang M, Zhang LJ. Establishment and characteristics of two syngeneic human osteosarcoma cell lines from primary tumor and skip metastases. *Acta Pharmacol Sin*. 2008 Mar;29(3):325-32.
**Other Major Achievements (e.g., Awards):**
In 2012, selected as a Young Core Faculty member for the Sun Yat-sen University Young Teacher Key Cultivation Project and the Outstanding Young Talent Support Program of the First Affiliated Hospital of Sun Yat-sen University. As Principal Investigator, has led 2 National Natural Science Foundation of China (General) projects, 3 Provincial Science and Technology Fund projects, and 3 University Special Fund projects.
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